Postdoc, Molecular Evolutionary Genetics
Position Location: U Paris 11 (Orsay) France
Position Description:
A CNRS post doc position is available in the lab Ecologie, Systematique et Evolution in the University of Paris 11 (Orsay). The targeted starting date is September 1, 2006, but is flexible. Our lab works on a broad range of projects in evolutionary biology, e.g. host-parasite co-evolution, biological invasions, reproductive systems, genome evolution, using experiments as well as mathematical modelling.
The project aims at detecting and studying the evolution of genes involved in the specialization and the speciation of a model parasite, Microbotryum violaceum, causing a sexually transmitted disease. This fungus constitutes a complex of sibling species, specialized on different Cayophyllaceae. This project aims at detecting genes that have rapidly evolved, and differently between close species, assuming that these genes will have important functions in speciation, specialisation, host-parasite co-evolution. EST libraries have been sequenced for 4 sibling species of Microbotryum. Signatures of positive or diversifying selection will be investigated by comparing orthologs among these genomes, e.g. using the ratio of synonymous vs non synonymous mutations. These genes will then systematically be sequenced in the whole species complex, and their genealogies will be compared to those of conserved genes. The variability of these genes will also be analysed within populations and compared to neutral markers (microsatellites, SNP, ..).
For this position, a Ph.D. in evolutionary biology, genomics, genetics, host-parasite ecology, or related field is required. Preference will be given to candidates with a strong background in population genetic theory, statistical genetics, evolutionary bioinformatics, and have experience in molecular biology, including standard DNA techniques (PCR and sequencing). Ideally, the candidate will be involved in various on-going projects in the lab, but also, he or she would be encouraged to design and be responsible for independent research that involves the collection, analysis and publishing of data. Knowledge of the French language is not required.
For more information regarding the position contact Dr. Tatiana Giraud tatiana.giraud@ese.u-psud.fr or Jacqui Shykoff jacqui.shykoff@ese.u-psud.fr. Please supply a statement of interest, curriculum vitae, and letters of recommendation.
Position Description:
A CNRS post doc position is available in the lab Ecologie, Systematique et Evolution in the University of Paris 11 (Orsay). The targeted starting date is September 1, 2006, but is flexible. Our lab works on a broad range of projects in evolutionary biology, e.g. host-parasite co-evolution, biological invasions, reproductive systems, genome evolution, using experiments as well as mathematical modelling.
The project aims at detecting and studying the evolution of genes involved in the specialization and the speciation of a model parasite, Microbotryum violaceum, causing a sexually transmitted disease. This fungus constitutes a complex of sibling species, specialized on different Cayophyllaceae. This project aims at detecting genes that have rapidly evolved, and differently between close species, assuming that these genes will have important functions in speciation, specialisation, host-parasite co-evolution. EST libraries have been sequenced for 4 sibling species of Microbotryum. Signatures of positive or diversifying selection will be investigated by comparing orthologs among these genomes, e.g. using the ratio of synonymous vs non synonymous mutations. These genes will then systematically be sequenced in the whole species complex, and their genealogies will be compared to those of conserved genes. The variability of these genes will also be analysed within populations and compared to neutral markers (microsatellites, SNP, ..).
For this position, a Ph.D. in evolutionary biology, genomics, genetics, host-parasite ecology, or related field is required. Preference will be given to candidates with a strong background in population genetic theory, statistical genetics, evolutionary bioinformatics, and have experience in molecular biology, including standard DNA techniques (PCR and sequencing). Ideally, the candidate will be involved in various on-going projects in the lab, but also, he or she would be encouraged to design and be responsible for independent research that involves the collection, analysis and publishing of data. Knowledge of the French language is not required.
For more information regarding the position contact Dr. Tatiana Giraud tatiana.giraud@ese.u-psud.fr or Jacqui Shykoff jacqui.shykoff@ese.u-psud.fr. Please supply a statement of interest, curriculum vitae, and letters of recommendation.